Delete all X 'tweets' from your profile, run on the 'replies' tab.

delete_tweets.js

const username = '@username';

const deleteAllTweets = async () => {
  const processed = new Set();
  const delay = ms => new Promise(r => setTimeout(r, ms + Math.random() * ms * 0.5));

  const processTweet = async (tweet) => {
    if (processed.has(tweet)) return;
    processed.add(tweet);

    const retweetBtn = tweet.querySelector('[data-testid="unretweet"]');
    if (retweetBtn) {
      retweetBtn.click();
      await delay(250);
      const confirm = document.querySelector('[data-testid="unretweetConfirm"]');
      if (confirm) confirm.click();
      return;
    }

    const caret = tweet.querySelector('[data-testid="caret"]');
    if (caret) {
      caret.click();
      await delay(250);
      const dropdown = document.querySelector('[data-testid="Dropdown"]');
      if (dropdown && dropdown.firstElementChild) {
        dropdown.firstElementChild.click();
        await delay(250);
        const confirm = document.querySelector('[data-testid="confirmationSheetConfirm"]');
        if (confirm) confirm.click();
      }
    }
  };

  while (true) {
    const tweets = Array.from(document.querySelectorAll('[data-testid="tweet"]'))
      .filter(t => !processed.has(t))
      .filter(t => t.innerText && t.innerText.includes(username));

    if (!tweets.length) {
      window.scrollTo({ top: document.body.scrollHeight, behavior: 'instant' });
      await delay(250);
      const fresh = document.querySelectorAll('[data-testid="tweet"]');
      if (![...fresh].some(t => !processed.has(t))) break;
      continue;
    }

    for (const tweet of tweets) {
      await processTweet(tweet);
    }

    // window.scrollTo({ top: document.body.scrollHeight, behavior: 'smooth' });
    await delay(250);
  }

  console.log('All tweets processed.');
};

deleteAllTweets();