My Sublime Text 2 Settings

Default (OSX).sublime-keymap

[
	{ "keys": ["ctrl+alt+f"], "command": "use_it" },

	{ "keys": ["ctrl+tab"], "command": "prev_view_in_stack" },
	{ "keys": ["ctrl+shift+tab"], "command": "next_view_in_stack" },

	{ "keys": ["ctrl+shift+j"], "command": "js_run" },

	// Paste and indent
	{ "keys": ["super+v"], "command": "paste_and_indent" },
	{ "keys": ["super+shift+v"], "command": "paste" },

	// Insert console.log
	{ "keys": ["super+shift+l"],
		"command": "insert_snippet",
		"args": {
			"contents": "console.log(${1:}$SELECTION);${0}"
		}
	},

	// Insert var_dump
	{ "keys": ["super+shift+k"],
		"command": "insert_snippet",
		"args": {
			"contents": "var_dump(${1:}$SELECTION);${0}"
		}
	}
]

st2-settings.sublime-settings

{
	"bold_folder_labels": true,
	"color_scheme": "Packages/Color Scheme - Default/Monokai.tmTheme",
	"draw_white_space": "all",
	"ensure_newline_at_eof_on_save": true,
	"file_exclude_patterns":
	[
		".DS_Store",
		".gitkeep"
	],
	"folder_exclude_patterns":
	[
		".git",
		".sass-cache",
		"tmp"
	],
	"font_face": "Source Code Pro",
	"font_size": 12.0,
	"highlight_line": true,
	"highlight_modified_tabs": true,
	"ignored_packages":
	[
		"Vintage"
	],
	"indent_guide_options": ["draw_normal", "draw_active"],
	"line_padding_bottom": 1,
	"line_padding_top": 1,
	"rulers":
	[
		80
	],
	"scroll_past_end": true,
	"tab_completion": true,
	"tab_size": 4,
	"theme": "Soda Light.sublime-theme",
	"translate_tabs_to_spaces": false,
	"trim_trailing_white_space_on_save": true
}

Oh, I'll try an italic font-style on that. Thanks for the tip!
Also when I'm on my MBA 11" I got a bigger font-size (13.0). This kinda correlates with 12.0 on my MBP.

Funny thing: I tried some of your settings as well, i.e. the trailing spaces/eof stuff. I was a bit baffled since they didn't work. Turns out they only don't work in settings files, i.e. a trailing space in settings won't be remove on save, also breaking the eof setting. I guess this is because trailing spaces are not allowed in settings files anyway or something.

Anyway, thanks for that. Very useful, actually saves me a package (Trailing Spaces).

Apart from the whitespace-settings in this file I'd encourage you to use editorconfig (http://editorconfig.org/) in projects. @sindresorhus made a great ST2 plugin for that.

Why "tab_completion": false, ?

@ttscoff suggested to add context to key shortcuts: https://gist.github.com/2951063#comment-354177

So you could use super+shift+l in javascript/php and it pastes the appropiate syntax.

"open_files_in_new_window": false is also handy.

For easier comments I use these two:

{ "keys": ["ctrl+q"], "command": "toggle_comment", "args": { "block": false } }, { "keys": ["ctrl+shift+c"], "command": "insert_snippet", "args": {"name": "Packages/User/InsertSectionComment.sublime-snippet"} },